Key Research Article
Title: "Primary familial brain calcification: update on molecular genetics"
Authors: Tadic V, Westenberger A, Klein C.
Published in: Current Neurology and Neuroscience Reports, 2019
This comprehensive review discusses the genetic basis of Fahr's Syndrome (PFBC), including:
- Identification of major causative genes (SLC20A2, PDGFRB, PDGFB, XPR1)
- Molecular mechanisms of brain calcification
- Current diagnostic approaches
- Potential therapeutic targets
Citation: Tadic, V., Westenberger, A. & Klein, C. Primary Familial Brain Calcification: Update on Molecular Genetics. Curr Neurol Neurosci Rep 19, 100 (2019).